If you’ve been scrolling through TikTok or browsing your favourite beauty platforms lately, you’ve probably noticed a new buzzword in skincare: exosomes. More brands are incorporating exosomes in skincare products, promising to transform dull, tired complexions into healthier, more resilient skin.
While they might sound like something straight out of a science textbook, exosomes are actually a powerful, skin-supporting ingredient that’s slowly becoming a staple in advanced formulas.
So, here’s everything to know about exosomes.
So, What Are Exosomes?
Source: Depositphotos
For years, skincare revolved around familiar names like hyaluronic acid, niacinamide, and peptides. However, as technology advances, brands are delving deeper into regenerative science — the kind that not only hydrates or brightens but also helps skin repair itself from within.
That’s where exosomes come in. They’re microscopic vesicles naturally released by our cells that carry proteins, peptides, lipids, and growth factors. Their job? To deliver essential signals that encourage regeneration and boost overall cellular health.
Additionally, exosomes are typically derived from plant stem cells, human stem cells, or yeast cultures, depending on the brand’s formulation and ethical approach.
While medical-grade exosomes are used in clinical therapies, cosmetic versions are purified and cell-free, meaning they don’t contain any live cells — just the beneficial molecules your skin can absorb and respond to. The result is a safe, sterile ingredient designed to support your skin’s natural repair process.
Products That Are Leading the Exosome Trend
With exosomes now becoming a must-have ingredient, a few brands have already carved out their space in this growing category. And here are some to consider:
Wardah Lift Regenerating Serum (Exosome + EGF-PDRN Serum)
Easily available at Watsons, the Wardah Lift Regenerating Serum is a powerful formula designed to reshape and redefine your facial contours.
Infused with exosomes, EGF, PDRN, and Proxylane, it helps skin regenerate, repair, and hydrate. Exosomes signal skin cells to rejuvenate, while growth factors boost collagen and elastin for stronger, firmer structure.
PDRN improves elasticity, and Proxylane deeply plumps and hydrates. Lightweight yet effective, this serum lifts, sculpts, and revitalises, leaving your skin looking visibly firmer, smoother, and more contoured.
Get this for RM89.90 from Watsons.
Dermatory Cica 2x Blemish Soothing Gauze Pad
Combat redness and irritation effortlessly with this soothing gauze pad. Infused with exosome cica, madecassoside, and niacinamide, these gel pads hydrate early irritation, calm redness, and smooth out blemishes for clearer, more radiant skin.
The non-slip, double-sided gauze fits perfectly for wiping or toner-packing, ensuring consistent soothing care from start to finish.
Quick and easy to use, they prep your skin for the next steps in your routine while providing instant relief. Ideal for acne-prone, sensitive, or irritated skin seeking hydration, balance, and a calmer, healthier-looking finish.
Get this for RM119 from Watsons.
Medicube One Day Pore Shot 2000/7500 Microneedling Serum
This high-performance serum is designed for those who want visible results without in-clinic procedures.
Medicube’s One Day Pore Shot delivers a concentrated dose of exosomes that target signs of ageing and skin fatigue. The lightweight formula sinks in quickly, leaving the skin feeling firm and hydrated.
With consistent use, it helps refine texture, improve elasticity, and revive radiance all while supporting the skin’s natural regeneration process.
Get this for RM150 from Medicube official website.
Sigi Skin Daylight Oasis Brightening Vitamin C Serum
Singapore-based brand Sigi Skin has also embraced exosome technology, blending it into their signature Daylight Oasis Brightening Vitamin C Serum.
Infused with exosomes, it helps deliver active ingredients deeper into the skin while boosting repair, collagen production, and overall radiance. The 15% L-Ascorbic Acid works to fade dark spots and even out skin tone, while Copper Tripeptide and antioxidant-rich superfoods strengthen and protect the barrier.
Lightweight yet potent, it’s designed for those looking to boost glow, reduce early signs of ageing, and maintain healthy, balanced skin without harsh or irritating ingredients.
Get this for RM346.20 from Sigi Skin official website.
Goop Beauty Exosome Hydration Therapy Serum
Revitalise your skin barrier with this gel-serum infused with over 3 million plant-based exosomes derived from cica leaf. The formula works deeply to hydrate and bounce back your skin with key actives like polyglutamic acid (even stronger than hyaluronic acid), snow mushroom and red sea moss.
It boosts moisture (+184% in a single use), calms redness, and enhances elasticity and radiance. Lightweight, fragrance-free, and suitable for sensitive skin, it’s a premium serum that delivers plumper, smoother, healthier-looking skin.
Get this for RM395.21 from FWRD.
Dr. Barbara Sturm Exoso-Metic Face Serum
Infused with lab-synthesised exosomes and epidermal growth factors, this high-performance serum activates skin’s natural renewal process.
It firms, smooths texture, and reduces uneven pigmentation while targeting fine lines, giving a visibly revitalised, youthful complexion.
Fragrance-free and formulated for all skin types, it’s ideal for those who want advanced anti-ageing benefits and cellular-level repair without invasive treatments.
Get this for RM2,225.67 from FWRD.
Dr.nineteen PoreXsome V.Peptox Jelly Toner
This jelly toner transforms into a refreshing liquid on contact, delivering hydration while refining pores.
Powered by advanced Pore Exosome technology and the 25,000 ppm PEPTOX complex with 13 peptides, it strengthens the skin’s structure, improves elasticity, and minimises the appearance of pores.
The toner absorbs quickly without any stickiness, leaving skin perfectly prepped for the next steps in your skincare routine. Plus, it’s ideal for combination, oily, or pore-prone skin seeking a smoother, clearer, and more even complexion.
Get this for RM112.70 from Stylevana.
Exosomes in Skincare: How They Work and Why They’re Game-Changing
In skincare, exosomes are used for their ability to “coach” the skin into behaving like it did when it was younger.
Unlike most creams or serums that work only on the surface, exosomes penetrate deeper to stimulate communication between cells. The result? Skin that feels smoother, firmer, and more resilient over time.
Source: Depositphotos
What makes them stand out is how they improve your skin’s overall function, not just one concern. Here’s how they work:
- Boosts Collagen and Elastin: Exosomes stimulate fibroblasts (the cells responsible for collagen production), which helps maintain firmness and elasticity. Over time, this can reduce the appearance of fine lines and sagging.
- Accelerates Repair: Because exosomes help skin cells communicate, they speed up recovery from irritation, acne scars, and environmental stress. Your skin heals more efficiently, which means less downtime between flare-ups or treatments.
- Strengthens the Skin Barrier: A resilient barrier is key to healthy skin. Exosomes support lipid production and cell turnover, improving your skin’s ability to retain moisture and defend against pollutants.
- Reduces Inflammation: If your skin often feels red, tight, or easily triggered, exosomes can help calm it down. Their soothing properties make them ideal for those with sensitivity or conditions like rosacea.
- Restore Radiance: By rejuvenating the skin at a cellular level, exosomes bring back that natural glow that often fades with stress, fatigue, or age. The result is skin that appears more even-toned, smoother, and visibly healthier.
